Mission Statement

The Center for Bioinformatics and Computational Biology aims to catalyze the development of new areas of study and expanded research opportunities in informatics areas related to the basic biological sciences, and applied medical research. Founded in 2002 as a joint enterprise spanning the Colleges of Engineering and Medicine and Science, the CBCB involves faculty from 7 Colleges, and more than 22 departments. It serves as a coordinating home for interdisciplinary research, undergraduate, pre- and post-doctoral training, as well as faculty recruiting and professional development. At the hub of an inherently interdisciplinary field, the goal of the CBCB is to assist in overcoming traditional disciplinary hurdles to collaboration and assist in utilizing state of the art instrumentation and analysis methods needed by 21st century biomedical and basic science research.


State of the art practice of bioinformatics involves collection, QC, analysis, archive and searching of molecular and clinical data. The CBCB has extensive data storage and processing capabilities, as well as a wealth of installed and maintained software analysis tools to enable research and experiment execution at the leading edge of modern biomedical research.

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Recent Publications

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge
C. A. Brownstein, A. H. Beggs, N. Homer, B....
Genome Biology. 2014 Mar. Volumbe 15 no. 3, p. R53
Altered Gene expression in dry age-related macular degeneration suggests early loss of choroidal endothelial cells
S. S. Whitmore, T. A. Braun, J. M. Skeie, C. M....
Molecular Vision. 2013 Nov. Vol 19 pp. 2274-2297
Non-exomic and synonymous variants in ABCA4 are an important cause of Stargardt disease
T. A. Braun, R. F. Mullins, A. H. Wagner, J. L....
Congenital myopathy is caused by mutation of HACD1
E. Muhammad, O. Reish, Y. Ohno, T. Scheetz, A....
Computational identification of operon-like transcriptional loci in eukaryotes.
Nannapaneni K, Ben-Shahar Y, Keen HL, Welsh MJ,...