Audioprofile Surfaces: The 21st Century Audiogram. Ann Otol Rhinol Laryngol

Authors: 
Taylor KR, Booth KT, Azaiez H, Sloan CM, Kolbe DL, Glanz EN, Shearer AE, DeLuca AP, Anand VN, Hildebrand MS, Simpson AC, Eppsteiner RW, Scheetz TE, Braun TA, Huygen PL, Smith RJ, Casavant TL.

OBJECTIVE: To present audiometric data in 3 dimensions by considering age as an
addition dimension.
METHODS: Audioprofile surfaces (APSs) were fitted to a set of audiograms by
plotting each measurement of an audiogram as an independent point in 3 dimensions
with the x, y, and z axes representing frequency, hearing loss in dB, and age,
respectively.
RESULTS: Using the Java-based APS viewer as a standalone application, APSs were
pre-computed for 34 loci. By selecting APSs for the appropriate genetic locus, a
clinician can compare this APS-generated average surface to a specific patient's
audiogram.
CONCLUSION: Audioprofile surfaces provide an easily interpreted visual
representation of a person's hearing acuity relative to others with the same
genetic cause of hearing loss. Audioprofile surfaces will support the generation
and testing of sophisticated hypotheses to further refine our understanding of
the biology of hearing.

Journal: 
Ann Otol Rhinol Laryngol
Additional Information: 
2015 Nov 3 pii: 0003489415614863 Epub
Pubmed ID: 
26530094